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125 Summaries
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Metabolic Syndrome, Endocrine, DiabetesTreatment of an Opposing Metabolic Situation: GLUT1- Deficiency Syndrome and Type 1 Diabetes
Glucose transporter type 1 deficiency syndrome (GLUT1-DS) is a rare genetic metabolic disorder resulting in impaired glucose transport across the blood–brain barrier and chronic cerebral...
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CancerSafety, Feasibility, and Effectiveness of Ketogenic Diet in Pediatric Patients with Brain Tumors: A Systematic Review
Researchers conducted a systematic review to assess the safety, feasibility, and potential effectiveness of a ketogenic diet in pediatric patients with brain tumors. The review included eight...
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Metabolic Syndrome, General Health, EndocrineMCT‑modified ketogenic diet as an adjunct to standard treatment regimen could alleviate clinical symptoms in women with endometriosis
Endometriosis often causes chronic pelvic pain, dyspareunia (pain during intercourse), and dyschezia (pain during defecation). Current treatments, including hormonal therapy, have limited long-term effectiveness, leading...
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General Health, Metabolic SyndromeThe Role of Beta-Hydroxybutyrate in Mitigating the Inflammatory and Metabolic Consequences of Uric Acid
Uric acid (UA) promotes inflammation primarily by activating the NLRP3 inflammasome. Elevated UA levels (hyperuricemia) are associated with gout, cardiovascular disease, and metabolic disorders. In...
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DiabetesmHealth low carbohydrate dietary intervention ameliorates glycaemic profile, blood pressure and weight status in people with type 2 diabetes
A single-arm study examined the effects of a mobile health (mHealth) low-carbohydrate dietary intervention delivered via the Defeat Diabetes app in 99 adults with type...
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General HealthThe role of β-hydroxybutyrate testing in ketogenic metabolic therapies
This narrative review examines the role of β-hydroxybutyrate (BHB) testing in ketogenic metabolic therapies (KMTs), which include ketogenic diets and fasting. KMTs induce nutritional ketosis,...
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Cardiovascular Diseaseβ-Hydroxybutyrate Alleviates Atherosclerotic Calcification by Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis via AMPK/Nrf2 Pathway
Atherosclerotic calcification (AC) contributes to arterial hardening and increased cardiovascular risk. Recent research has shown that the ketone body β-hydroxybutyrate (BHB) has protective effects on...
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DiabetesSustained metabolic improvements in a remotely delivered ketogenic nutrition programme for veterans with type 2 diabetes: A 3-year observational study
Veterans with type 2 diabetes (T2D) face unique challenges, including high rates of comorbidities and barriers to in-person care. This 3-year observational study evaluated the...
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Psychiatric DisordersRemission of obsessive-compulsive disorder using ketogenic metabolic therapy in support of exposure and response prevention: a retrospective case report
This case report examines the use of ketogenic metabolic therapy as an adjunct to exposure and response prevention (ERP) in the treatment of a 26-year-old...
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