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166 Summaries
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CancerVery Low-Carbohydrate Ketogenic Diet in Treatment-Naïve Women with Endometrial Cancer and Overweight: A Randomized Feasibility Study
Endometrial cancer is strongly associated with obesity, insulin resistance, and hyperinsulinemia. More than 90% of endometrial tumors contain alterations in the PI3K signaling pathway, which...
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Diabetes, Endocrine, Gastrointestinal Health, Metabolic SyndromeEffect of diet macronutrient content on the cardiometabolic response to weight loss: A randomized clinical trial
In this 2026 randomized clinical trial, researchers compared three different dietary approaches in adults with metabolically unhealthy obesity, defined by obesity, prediabetes, and hepatic steatosis....
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Gastrointestinal Health, Metabolic Syndrome, EndocrineReduced risk of liver-related events among patients receiving individualized nutrition-focused remote care in the United States
This large, real-world matched cohort study examined whether an individualized, nutrition-focused remote care program could reduce the risk of liver disease in adults with type...
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CancerPostoperative recurrence of pancreatic cancer controlled for 9 months solely by severe carbohydrate restriction: ketogenic diet
This case report documents the experience of a 60-year-old female patient with pancreatic ductal adenocarcinoma (PDAC), whose metastatic recurrence was stabilized for nine months through...
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CancerKetogenic diet as a metabolic vehicle enhancing the therapeutic efficacy of mebendazole and devimistat in juvenile syngeneic high-grade glioma
Pediatric high-grade gliomas (HGGs) are aggressive brain tumors with poor outcomes and substantial treatment-related toxicity. Because glioma cells rely heavily on glucose and glutamine metabolism,...
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Immunological, Musculoskeletal, NeurologyFasting Mimicking Diets Reverse Accelerated Biological Aging in Multiple Sclerosis
A secondary analysis of previously published studies explored whether fasting-mimicking diets (FMDs) could slow or reverse accelerated biological aging in people with multiple sclerosis. Researchers...
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DiabetesFive-Year outcomes of a digitally delivered carbohydrate-reduced nutrition intervention for prediabetes: durability of diabetes prevention
Prediabetes affects hundreds of millions of people worldwide and substantially increases the risk of developing type 2 diabetes (T2D), cardiovascular disease, chronic kidney disease, and...
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Cancer, Metabolic SyndromeThe glucose ketone index: a proposed quantitative biomarker to support cancer and chronic disease prevention and management
Mitochondrial dysfunction is increasingly recognized as a common feature of many chronic diseases, including cancer, type 2 diabetes, cardiovascular disease, obesity, neurodegenerative disorders, and some...
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Musculoskeletal, NeurologyFasting, ketogenic, and anti-inflammatory diets in multiple sclerosis: a randomized controlled trial with 18-month follow-up
A randomized controlled trial examined the effects of a fasting diet (FD) and a ketogenic diet (KD) compared to a standard healthy diet (SD) in individuals with relapsing-remitting multiple sclerosis (MS), a chronic...
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