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155 Summaries
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Psychiatric DisordersMetabolic Improvements with a Ketogenic Diet Correlate with Symptom Improvement in Psychosis: A Randomized Controlled Trial
People with schizophrenia-spectrum disorders and bipolar I disorder experience high rates of metabolic dysfunction, which may contribute to both poor physical health and persistent psychiatric...
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Metabolic Syndrome, ObesityPersonalizing Obesity Treatment: Real-World Comparison of a Very-Low-Calorie Ketogenic Diet Versus a Whole-Food Mediterranean Ketogenic
This real-world prospective study compared two ketogenic approaches for obesity management: a very-low-calorie ketogenic diet (VLCKD) using meal replacements and a whole-food Mediterranean ketogenic diet...
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Cardiovascular Disease, Metabolic Syndrome, ObesityComparative Effects of Time-Restricted Eating and the Ketogenic Diet on Cardiovascular Risk in Individuals with Obesity: A Longitudinal Analysis of Metabolic, Anthropometric, and Lifestyle Factors
This 12-week interventional, non-randomized clinical study evaluated the comparative effectiveness of two popular dietary strategies – the modified Ketogenic Diet (KD) and Time-Restricted Eating (TRE)...
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Psychiatric DisordersMedically supervised ketogenic diet as an adjunctive treatment for moderate to severe depression: A pilot study
Major depressive disorder is a prevalent and often treatment-resistant psychiatric condition, frequently co-occurring with metabolic dysfunction. Given growing interest in metabolic interventions, this pilot study explored...
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Psychiatric DisordersSymptom impact and safety of ketogenic therapy in adults with anorexia nervosa: a feasibility trial
Despite weight restoration, many people with anorexia nervosa (AN) continue to experience persistent eating disorder symptoms and high rates of relapse. Researchers investigated whether a...
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DiabetesGreater reduction in the proinsulin-C-peptide ratio with a ketogenic vs control diet in patients with type 2 diabetes
This randomized controlled trial evaluated whether a ketogenic diet (KD) reduces beta-cell stress to a greater extent than a low-fat diet (LFD) in adults with...
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ObesityEffect of a ketogenic diet, time-restricted eating, or alternate-day fasting on weight loss in adults with obesity: a randomized clinical trial
A 3-month randomized clinical trial (RCT) assessed the effectiveness of four dietary interventions compared to a calorie-restricted Mediterranean diet in promoting weight loss in adults...
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General Health, Metabolic SyndromeKetosis Suppression and Ageing (KetoSAge): The Effect of Suppressing Ketosis on GKI and Liver Biomarkers in Healthy Females
A non-randomized cross-over trial examined the effects of short-term ketosis suppression on liver biomarkers and metabolic parameters in ten healthy, lean, premenopausal women who had...
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Musculoskeletal, Metabolic Syndrome, Exercise & Sports PerformanceLow‑carbohydrate ketogenic diet in McArdle’s disease: a single‑blinded randomized controlled trial
McArdle disease, also known as glycogen storage disease type 5 (GSD5 ), is a rare genetic disorder resulting from a deficiency of muscle glycogen phosphorylase. This...
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