Reasearch
150 Summaries
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DiabetesGreater reduction in the proinsulin-C-peptide ratio with a ketogenic vs control diet in patients with type 2 diabetes
This randomized controlled trial evaluated whether a ketogenic diet (KD) reduces beta-cell stress to a greater extent than a low-fat diet (LFD) in adults with...
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ObesityEffect of a ketogenic diet, time-restricted eating, or alternate-day fasting on weight loss in adults with obesity: a randomized clinical trial
A 3-month randomized clinical trial (RCT) assessed the effectiveness of four dietary interventions compared to a calorie-restricted Mediterranean diet in promoting weight loss in adults...
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General Health, Metabolic SyndromeKetosis Suppression and Ageing (KetoSAge): The Effect of Suppressing Ketosis on GKI and Liver Biomarkers in Healthy Females
A non-randomized cross-over trial examined the effects of short-term ketosis suppression on liver biomarkers and metabolic parameters in ten healthy, lean, premenopausal women who had...
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Metabolic Syndrome, Musculoskeletal, Exercise & Sports PerformanceLow‑carbohydrate ketogenic diet in McArdle’s disease: a single‑blinded randomized controlled trial
McArdle disease, also known as glycogen storage disease type 5 (GSD5 ), is a rare genetic disorder resulting from a deficiency of muscle glycogen phosphorylase. This...
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Cancer, Exercise & Sports PerformanceTargeting differential energy substrate metabolism on a therapeutic ketogenic diet: a case report
This case report examines the relationship between exercise intensity and blood ketone levels in a 44-year-old male patient with glioblastoma who followed a therapeutic ketogenic...
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Exercise & Sports PerformanceThe Effects of 31-Day Exogenous Ketone Consumption on Running Performance, Cognitive Function, Metabolism, Body Composition, Hemodynamics, and Mood in Recreational Runners: A Randomized-Control Trial
Exogenous ketone supplements can rapidly raise circulating beta-hydroxybutyrate (BHB), but their longer-term effects on exercise performance, cognition, and metabolic health remain unclear. This randomized controlled...
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Psychiatric DisordersKetogenic metabolic therapy for treatment-resistant post-traumatic stress disorder (PTSD): a retrospective case report
This retrospective case report examined the use of ketogenic metabolic therapy (KMT) in a 45-year-old woman with treatment-resistant post-traumatic stress disorder (PTSD) related to military sexual trauma....
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Cardiovascular Disease, Obesity, Metabolic Syndrome, General HealthLow-Calorie, High-Protein Ketogenic Diet Versus Low-Calorie, Low-Sodium, and High-Potassium Mediterranean Diet in Overweight Patients and Patients with Obesity with High-Normal Blood Pressure or Grade I Hypertension: The Keto-Salt Pilot Study
This pilot study examined the effects of two calorie-restricted diets on blood pressure and metabolic health in overweight or obese adults with mildly elevated blood...
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Psychiatric DisordersA Ketogenic Diet for Treatment-Resistant Depression: A Randomized Clinical Trial
Treatment-resistant depression (TRD), defined as a lack of meaningful response to at least two adequate antidepressant treatments, remains a significant clinical challenge. Emerging evidence suggests that...
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