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153 Summaries
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Cardiovascular Disease, Metabolic Syndrome, ObesityComparative Effects of Time-Restricted Eating and the Ketogenic Diet on Cardiovascular Risk in Individuals with Obesity: A Longitudinal Analysis of Metabolic, Anthropometric, and Lifestyle Factors
This 12-week interventional, non-randomized clinical study evaluated the comparative effectiveness of two popular dietary strategies – the modified Ketogenic Diet (KD) and Time-Restricted Eating (TRE)...
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Psychiatric DisordersMedically supervised ketogenic diet as an adjunctive treatment for moderate to severe depression: A pilot study
Major depressive disorder is a prevalent and often treatment-resistant psychiatric condition, frequently co-occurring with metabolic dysfunction. Given growing interest in metabolic interventions, this pilot study explored...
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Psychiatric DisordersSymptom impact and safety of ketogenic therapy in adults with anorexia nervosa: a feasibility trial
Despite weight restoration, many people with anorexia nervosa (AN) continue to experience persistent eating disorder symptoms and high rates of relapse. Researchers investigated whether a...
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DiabetesGreater reduction in the proinsulin-C-peptide ratio with a ketogenic vs control diet in patients with type 2 diabetes
This randomized controlled trial evaluated whether a ketogenic diet (KD) reduces beta-cell stress to a greater extent than a low-fat diet (LFD) in adults with...
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ObesityEffect of a ketogenic diet, time-restricted eating, or alternate-day fasting on weight loss in adults with obesity: a randomized clinical trial
A 3-month randomized clinical trial (RCT) assessed the effectiveness of four dietary interventions compared to a calorie-restricted Mediterranean diet in promoting weight loss in adults...
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General Health, Metabolic SyndromeKetosis Suppression and Ageing (KetoSAge): The Effect of Suppressing Ketosis on GKI and Liver Biomarkers in Healthy Females
A non-randomized cross-over trial examined the effects of short-term ketosis suppression on liver biomarkers and metabolic parameters in ten healthy, lean, premenopausal women who had...
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Exercise & Sports Performance, Musculoskeletal, Metabolic SyndromeLow‑carbohydrate ketogenic diet in McArdle’s disease: a single‑blinded randomized controlled trial
McArdle disease, also known as glycogen storage disease type 5 (GSD5 ), is a rare genetic disorder resulting from a deficiency of muscle glycogen phosphorylase. This...
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Exercise & Sports Performance, CancerTargeting differential energy substrate metabolism on a therapeutic ketogenic diet: a case report
This case report examines the relationship between exercise intensity and blood ketone levels in a 44-year-old male patient with glioblastoma who followed a therapeutic ketogenic...
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Exercise & Sports PerformanceThe Effects of 31-Day Exogenous Ketone Consumption on Running Performance, Cognitive Function, Metabolism, Body Composition, Hemodynamics, and Mood in Recreational Runners: A Randomized-Control Trial
Exogenous ketone supplements can rapidly raise circulating beta-hydroxybutyrate (BHB), but their longer-term effects on exercise performance, cognition, and metabolic health remain unclear. This randomized controlled...
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