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169 Summaries
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ObesityDefining a ketone threshold for weight loss: evidence from 14 day daily β-hydroxybutyrate monitoring in 217 subjects on a ketogenic diet
Although nutritional ketosis is considered central to the effectiveness of ketogenic diets (KDs), the minimum blood β-hydroxybutyrate (βHB) concentration associated with successful weight loss has...
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General HealthKetogenic Diet and Hyperandrogenism in Women with Polycystic Ovary Syndrome: A Meta-Analysis
Polyendocrine metabolic ovarian syndrome (PMOS; formerly polycystic ovary syndrome [PCOS]) is commonly associated with hyperandrogenism, obesity, and insulin resistance. Researchers conducted a systematic review and...
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Cardiovascular Disease, ObesityRetrospective Review of the Safety and Effectiveness of a Low Carbohydrate Ketogenic Diet Intervention in Patients with Overweight or Obesity and Heart Failure
This retrospective study evaluated the safety and effectiveness of a low-carbohydrate ketogenic diet (LCKD) in adults with overweight or obesity and heart failure (HF), including...
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CancerVery Low-Carbohydrate Ketogenic Diet in Treatment-Naïve Women with Endometrial Cancer and Overweight: A Randomized Feasibility Study
Endometrial cancer is strongly associated with obesity, insulin resistance, and hyperinsulinemia. More than 90% of endometrial tumors contain alterations in the PI3K signaling pathway, which...
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Gastrointestinal Health, Diabetes, Endocrine, Metabolic SyndromeEffect of diet macronutrient content on the cardiometabolic response to weight loss: A randomized clinical trial
In this 2026 randomized clinical trial, researchers compared three different dietary approaches in adults with metabolically unhealthy obesity, defined by obesity, prediabetes, and hepatic steatosis....
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Metabolic Syndrome, Gastrointestinal Health, EndocrineReduced risk of liver-related events among patients receiving individualized nutrition-focused remote care in the United States
This large, real-world matched cohort study examined whether an individualized, nutrition-focused remote care program could reduce the risk of liver disease in adults with type...
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CancerPostoperative recurrence of pancreatic cancer controlled for 9 months solely by severe carbohydrate restriction: ketogenic diet
This case report documents the experience of a 60-year-old female patient with pancreatic ductal adenocarcinoma (PDAC), whose metastatic recurrence was stabilized for nine months through...
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CancerKetogenic diet as a metabolic vehicle enhancing the therapeutic efficacy of mebendazole and devimistat in juvenile syngeneic high-grade glioma
Pediatric high-grade gliomas (HGGs) are aggressive brain tumors with poor outcomes and substantial treatment-related toxicity. Because glioma cells rely heavily on glucose and glutamine metabolism,...
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Musculoskeletal, Neurology, ImmunologicalFasting Mimicking Diets Reverse Accelerated Biological Aging in Multiple Sclerosis
A secondary analysis of previously published studies explored whether fasting-mimicking diets (FMDs) could slow or reverse accelerated biological aging in people with multiple sclerosis. Researchers...
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