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Ketone Bodies as Signaling Molecules

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John Newman, MD, PhD

John Newman is Assistant Professor at the Buck Institute for Research on Aging and in the Division of Geriatrics at UCSF. His career goal is to translate our expanding understanding of aging biology to improve the care and help maintain the independence of older adults. His research at Buck studies the molecular details of how diet and fasting regulate the genes and pathways that in turn control aging, focusing on the ketone body beta-hydroxybutyrate and how its molecular signaling activities involving epigenetics and inflammation regulate aging and memory in mice.

Dr. Newman is also a geriatrician who cares for hospitalized older adults at UCSF and the San Francisco VA Medical Center, focusing on preserving mobility and preventing delirium. He completed an MD/PhD at the University of Washington, then residency and fellowship training at UCSF. He is an NIA Beeson Scholar. www.buckinstitute.org/lab/newman-lab/

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