83 Summaries
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General HealthEfficacy, Safety, and Tolerability of a Very Low-Calorie Ketogenic Diet in Women with Obesity and Symptomatic Knee Osteoarthritis: A Pilot Interventional Study
Obesity is a significant risk factor for knee osteoarthritis (OA), and weight loss is critical for OA management. This pilot study evaluated the effects of...
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Cardiovascular Disease, General Health
The ketogenic diet has the potential to decrease all-cause mortality without a concomitant increase in cardiovascular-related mortality
The ketogenic diet continues to receive interest for its ability to improve insulin sensitivity and glycemic control, promote weight loss, reduce inflammation, and enhance cognitive...
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General Health
Effect of ketogenic diets on insulin-like growth factor (IGF)-1 in humans: A systematic review and meta-analysis
During aging, the body’s nutrient-sensing systems, especially the growth hormone and IGF-1 pathways, can become disrupted. While these pathways promote cell growth, elevated levels are also...
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General Health
RenNu, a Dietary Program for Individuals with Autosomal-Dominant Polycystic Kidney Disease Implementing a Sustainable, Plant-Focused, Kidney-Safe, Ketogenic Approach with Avoidance of Renal Stressors
Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited cause of kidney failure, with limited treatment options available that do not achieve regression. Recent...
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Endocrine, Cancer
The genetically predicted causal associations between circulating 3-hydroxybutyrate levels and malignant neoplasms: A pan-cancer Mendelian randomization study
Emerging research suggests that β-hydroxybutyrate (BHB), a ketone body produced via hepatic fatty acid β-oxidation, may have protective effects against certain cancers. This study aimed...
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Cardiovascular Disease
Ketosis prevents abdominal aortic aneurysm rupture through C–C chemokine receptor type 2 downregulation and enhanced extracellular matrix balance
Abdominal aortic aneurysms (AAAs) are a serious condition often linked to aging, with rupture leading to high mortality rates. Currently, there is no effective medical...
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General Health
Nutrient analysis of three low-carbohydrate diets differing in carbohydrate content
Low-carbohydrate diets have proven effective in managing conditions like type 2 diabetes, polycystic ovarian syndrome, and obesity. However, there are concerns about their effects on...
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Epilepsy, Neurology
Short-term effectiveness and side effects of ketogenic diet for drug-resistant epilepsy in children with genetic epilepsy syndromes
Drug-resistant epilepsy (DRE) affects approximately one-third of all epilepsy patients and is defined by the failure of two or more anti-seizure medications to control seizures. Surgical or...
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Diabetes
5-Year effects of a novel continuous remote care model with carbohydrate-restricted nutrition therapy including nutritional ketosis in type 2 diabetes: An extension study
Over the past two decades, research has challenged the view that type 2 diabetes is an irreversible, progressive condition. New evidence suggests that sustained remission,...
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