Keto Diet Bettered Fatigue, Depression in MS

May 19, 2022

Brain ImageA ketogenic diet was safe, tolerable, and provided clinical benefits to people with relapsing multiple sclerosis (MS), a phase II study found.

Relapsing MS patients enrolled in the 6-month prospective ketogenic intervention had significant reductions in fat mass and showed a nearly 50% decline in fatigue and depression scores, reported J. Nicholas Brenton, MD, of the University of Virginia in Charlottesville, at the American Academy of Neurology annual meeting, held in Seattle and online.

MS quality of life (QoL) physical health and mental health composite scores increased while participants were on the diet, and improvements were seen in Expanded Disability Status Scale (EDSS) scores, Brenton added. The findings were published simultaneously in the Journal of Neurology, Neurosurgery, and Psychiatry.

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