Effect of a low-carbohydrate diet on pain and quality of life in female patients with lipedema: a randomized controlled trial

Lipedema is a chronic condition involving abnormal fat accumulation and pain in the lower body. It primarily affects women and is often underdiagnosed, with treatment...

A three-week ketogenic diet increases skeletal muscle insulin sensitivity in individuals with obesity – a randomized, controlled crossover trial

Ketogenic diets are known for promoting weight loss, improving glycemic control, and providing other metabolic health benefits. Although the mechanism behind these beneficial effects isn’t...

At any level of adiposity, relatively elevated leptin concentrations are associated with decreased insulin sensitivity

Leptin Levels and Glucose Homeostasis: Insights from the RISC Study A recent study explores the role of leptin levels in glucose homeostasis among individuals with...

Metabolic syndrome as an independent risk factor for glaucoma: A nationally representative study

A new study in Diabetology & Metabolic Syndrome has investigated the link between metabolic syndrome and the risk of developing primary open-angle glaucoma, a condition...

Ketonemia variability through menstrual cycle in patients undergoing classic ketogenic diet

Impact of Menstrual Cycle on Ketone Levels in Ketogenic Dietary Therapies Ketogenic dietary therapies are non-pharmacologic treatments primarily used for drug-resistant epilepsy and other neurological...

Impaired glucose utilization in the brain of patients with delirium following hip fracture

Exploring Metabolic Factors in Delirium Among Elderly Patients For over six decades, insufficient cerebral energy metabolism has been proposed as a cause of delirium, supported...

Adherence to ketogenic diet in lifestyle interventions in adults with overweight or obesity and type 2 diabetes: a scoping review

For better evaluation and comparison of ketogenic therapy studies, a standardized protocol for assessing ketones needs to be established, including what ketone bodies to measure,...

Effects of Ketogenic Diet on Reproductive Hormones in Women With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome (PCOS) is a complex disorder in women characterized by features such as irregular ovulation, high levels of male hormones, and polycystic ovaries....

Glucose metabolism, hippocampal subfields and cognition in first-episode and never-treated schizophrenia

Abnormal glucose metabolism and cognitive decline occur in the early stage of Schizophrenia. In this study recently published in the International Journal of Clinical Health...

Serum and CSF metabolomics analysis shows Mediterranean Ketogenic Diet mitigates risk factors of Alzheimer’s disease

Alzheimer’s disease is a progressive neurodegenerative disorder that leads to severe cognitive decline and memory loss. Despite new medications, it has no cure. Because suboptimal...

An open-label, randomized controlled trial to assess a ketogenic diet in critically ill patients with sepsis

Sepsis is a deadly immune response condition that remains highly fatal despite advanced care. The current standard of carbohydrate-rich feeding in critically ill patients may...

Ketosis Suppression and Ageing (KetoSAge) Part 2: The Effect of Suppressing Ketosis on Biomarkers Associated with Ageing, HOMA-IR, Leptin, Osteocalcin, and GLP-1, in Healthy Females

Part 2 of a recent clinical trial has been published, focusing on how short-term suppression of nutritional ketosis (NK) affects aging-related metabolic health markers and...

Ketosis Suppression and Ageing (KetoSAge): The Effects of Suppressing Ketosis in Long Term Keto-Adapted Non-Athletic Females

A study published in the International Journal of Molecular Sciences bolsters the hypothesis that the natural state of humans may be nutritional ketosis, providing evidence...

Addressing Pain Using a Mediterranean Ketogenic Nutrition Program in Older Adults with Mild Cognitive Impairment

Chronic pain is common among older adults and can impair their physical and mental well-being, leading to a reduced quality of life. A recent study...

Hyperinsulinemia is a probable trigger for weight gain and hyperphagia in individuals with Prader-Willi syndrome

This study explores the role of insulin in weight gain and hyperphagia (excessive appetite) in children with Prader-Willi syndrome (PWS), a primary genetic cause of...

Ketogenic Diet Induced Shifts in the Gut Microbiome Associate with Changes to Inflammatory Cytokines and Brain-Related miRNAs in Children with Autism Spectrum Disorder

Autism Spectrum Disorder (ASD) affects over 1 in 100 children globally and is associated with immune system changes, inflammation, and gastrointestinal issues. Abnormal gut flora...

Sleep duration and insulin resistance in obese adolescents with metabolic syndrome: is there a correlation?

🔬 Sleep Duration and Insulin Resistance in Obese Adolescents 🛌 A recent study by Widjaja et al. (2023) investigates the relationship between sleep duration and...

Therapeutic Carbohydrate Restriction as a Metabolic Modality for the Prevention and Treatment of Abnormal Uterine Bleeding

🔬 Therapeutic Carbohydrate Restriction for Gynecologic Health 🌾 Abnormal uterine bleeding (AUB) is a significant health concern, affecting one-third of women by age 60 and...

Ketogenic diet ameliorates attention deficit hyperactivity disorder in rats via regulating gut microbiota

🔬 Ketogenic Diet: A Potential Alternative for ADHD Treatment? 🥑 Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent behavioral disorder affecting children and often continuing...

Arthritis and Insulin Resistance Study: Higher TyG index values are linked to increased arthritis risk in younger adults without obesity or diabetes

🔬 Triglyceride-Glucose (TyG) Index and Arthritis Risk 🦴 A recent study by Yan et al. (2023) investigates the relationship between the TyG index, a biomarker...

The effect of a ketogenic diet versus Mediterranean diet on clinical and biochemical markers of inflammation in patients with obesity and psoriatic arthritis: a randomized crossover trial

Psoriasis and psoriatic arthritis are autoimmune conditions characterized by chronic inflammation and significant impacts on quality of life. Although the impact of diet on disease...

Effects of ketogenic diet on health outcomes: an umbrella review of meta-analyses of randomized clinical trials

In a comprehensive analysis of multiple studies and meta-analyses, researchers evaluated the impact of a ketogenic diet on various health outcomes. The results demonstrated positive...

Effect of Dietary Approaches on Glycemic Control in Patients with Type 2 Diabetes: A Systematic Review with Network Meta-Analysis of Randomized Trials

This network meta-analysis aimed to compare the impacts of various dietary patterns on the glycemic control of Type 2 diabetes (T2DM) patients. Relevant studies were...

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