85 Summaries
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Diabetes
Impact of Continuous Glucose Monitoring Versus Blood Glucose Monitoring to Support a Carbohydrate-Restricted Nutrition Intervention in People with Type 2 Diabetes
Ketogenic interventions supported by remote, continuous care have shown positive outcomes in individuals with type 2 diabetes (T2D). This study compared the use of continuous...
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General Health
Exposure to sugar rationing in the first 1000 days of life protected against chronic disease
The impact of early-life sugar exposure on long-term health has become a critical area of research, especially as chronic diseases like diabetes and hypertension continue...
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General Health
Efficacy, Safety, and Tolerability of a Very Low-Calorie Ketogenic Diet in Women with Obesity and Symptomatic Knee Osteoarthritis: A Pilot Interventional Study
Obesity is a significant risk factor for knee osteoarthritis (OA), and weight loss is critical for OA management. This pilot study evaluated the effects of...
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General Health, Cardiovascular Disease
The ketogenic diet has the potential to decrease all-cause mortality without a concomitant increase in cardiovascular-related mortality
The ketogenic diet continues to receive interest for its ability to improve insulin sensitivity and glycemic control, promote weight loss, reduce inflammation, and enhance cognitive...
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General Health
Effect of ketogenic diets on insulin-like growth factor (IGF)-1 in humans: A systematic review and meta-analysis
During aging, the body’s nutrient-sensing systems, especially the growth hormone and IGF-1 pathways, can become disrupted. While these pathways promote cell growth, elevated levels are also...
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General Health
RenNu, a Dietary Program for Individuals with Autosomal-Dominant Polycystic Kidney Disease Implementing a Sustainable, Plant-Focused, Kidney-Safe, Ketogenic Approach with Avoidance of Renal Stressors
Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited cause of kidney failure, with limited treatment options available that do not achieve regression. Recent...
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Endocrine, Cancer
The genetically predicted causal associations between circulating 3-hydroxybutyrate levels and malignant neoplasms: A pan-cancer Mendelian randomization study
Emerging research suggests that β-hydroxybutyrate (BHB), a ketone body produced via hepatic fatty acid β-oxidation, may have protective effects against certain cancers. This study aimed...
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Cardiovascular Disease
Ketosis prevents abdominal aortic aneurysm rupture through C–C chemokine receptor type 2 downregulation and enhanced extracellular matrix balance
Abdominal aortic aneurysms (AAAs) are a serious condition often linked to aging, with rupture leading to high mortality rates. Currently, there is no effective medical...
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General Health
Nutrient analysis of three low-carbohydrate diets differing in carbohydrate content
Low-carbohydrate diets have proven effective in managing conditions like type 2 diabetes, polycystic ovarian syndrome, and obesity. However, there are concerns about their effects on...