Reasearch
122 Summaries
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General Health, Metabolic SyndromeThe Role of Beta-Hydroxybutyrate in Mitigating the Inflammatory and Metabolic Consequences of Uric Acid
Uric acid (UA) promotes inflammation primarily by activating the NLRP3 inflammasome. Elevated UA levels (hyperuricemia) are associated with gout, cardiovascular disease, and metabolic disorders. In...
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Diabetes
mHealth low carbohydrate dietary intervention ameliorates glycaemic profile, blood pressure and weight status in people with type 2 diabetes
A single-arm study examined the effects of a mobile health (mHealth) low-carbohydrate dietary intervention delivered via the Defeat Diabetes app in 99 adults with type...
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General Health
The role of β-hydroxybutyrate testing in ketogenic metabolic therapies
This narrative review examines the role of β-hydroxybutyrate (BHB) testing in ketogenic metabolic therapies (KMTs), which include ketogenic diets and fasting. KMTs induce nutritional ketosis,...
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Cardiovascular Disease
β-Hydroxybutyrate Alleviates Atherosclerotic Calcification by Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis via AMPK/Nrf2 Pathway
Atherosclerotic calcification (AC) contributes to arterial hardening and increased cardiovascular risk. Recent research has shown that the ketone body β-hydroxybutyrate (BHB) has protective effects on...
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Diabetes
Sustained metabolic improvements in a remotely delivered ketogenic nutrition programme for veterans with type 2 diabetes: A 3-year observational study
Veterans with type 2 diabetes (T2D) face unique challenges, including high rates of comorbidities and barriers to in-person care. This 3-year observational study evaluated the...
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Psychiatric Disorders
Remission of obsessive-compulsive disorder using ketogenic metabolic therapy in support of exposure and response prevention: a retrospective case report
This case report examines the use of ketogenic metabolic therapy as an adjunct to exposure and response prevention (ERP) in the treatment of a 26-year-old...
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Psychiatric Disorders
Transdiagnostic remission of psychiatric comorbidity in post-traumatic stress disorder, ADHD, and binge-eating disorder using ketogenic metabolic therapy: a retrospective case report
This case report describes a 12-week ketogenic metabolic therapy (KMT) intervention in a 38-year-old woman with multiple comorbidities: treatment-resistant PTSD, ADHD, binge-eating disorder, depression, anxiety,...
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General Health, Metabolic Syndrome, Psychiatric Disorders
TOWARD: a metabolic health intervention that improves food addiction and binge eating symptoms
This study evaluated a telemedicine-based metabolic health program designed to reduce food addiction and binge eating symptoms through a structured, multi-component intervention called TOWARD, which...
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Diabetes
Effects of continuous glucose monitoring versus blood glucose monitoring during a carbohydrate-restricted nutrition intervention in people with type 2 diabetes: 6-month follow-up outcomes from a randomized clinical trial
The IGNITE study (Impact of Glucose moNitoring and nutrItion on Time in rangE) was a randomized clinical trial that compared continuous glucose monitoring (CGM) and...
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