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All posts tagged with “nutritional-ketosis” Clear Tags
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CancerVery Low-Carbohydrate Ketogenic Diet in Treatment-Naïve Women with Endometrial Cancer and Overweight: A Randomized Feasibility Study
Endometrial cancer is strongly associated with obesity, insulin resistance, and hyperinsulinemia. More than 90% of endometrial tumors contain alterations in the PI3K signaling pathway, which...
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Endocrine, Gastrointestinal Health, Metabolic SyndromeReduced risk of liver-related events among patients receiving individualized nutrition-focused remote care in the United States
This large, real-world matched cohort study examined whether an individualized, nutrition-focused remote care program could reduce the risk of liver disease in adults with type...
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CancerKetogenic diet as a metabolic vehicle enhancing the therapeutic efficacy of mebendazole and devimistat in juvenile syngeneic high-grade glioma
Pediatric high-grade gliomas (HGGs) are aggressive brain tumors with poor outcomes and substantial treatment-related toxicity. Because glioma cells rely heavily on glucose and glutamine metabolism,...
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DiabetesFive-Year outcomes of a digitally delivered carbohydrate-reduced nutrition intervention for prediabetes: durability of diabetes prevention
Prediabetes affects hundreds of millions of people worldwide and substantially increases the risk of developing type 2 diabetes (T2D), cardiovascular disease, chronic kidney disease, and...
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Cancer, Metabolic SyndromeThe glucose ketone index: a proposed quantitative biomarker to support cancer and chronic disease prevention and management
Mitochondrial dysfunction is increasingly recognized as a common feature of many chronic diseases, including cancer, type 2 diabetes, cardiovascular disease, obesity, neurodegenerative disorders, and some...
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Diabetes, EndocrineBroad-Spectrum Effects of Carbohydrate Reduction on Inflammatory and Immune Mediators in Type 2 Diabetes
This study examined the long-term effects of carbohydrate reduction with nutritional ketosis on inflammatory and immune markers in adults with type 2 diabetes (T2D) and...
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Cancer, NeurologyIntensive Multimodal Ketogenic Metabolic Therapy in Glioblastoma: A Clinical Trial
Glioblastoma (GBM), isocitrate dehydrogenase (IDH)-wildtype, is the most common and aggressive primary brain tumor in adults, with a median overall survival of approximately 11–14 months...
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Psychiatric DisordersMetabolic Improvements with a Ketogenic Diet Correlate with Symptom Improvement in Psychosis: A Randomized Controlled Trial
People with schizophrenia-spectrum disorders and bipolar I disorder experience high rates of metabolic dysfunction, which may contribute to both poor physical health and persistent psychiatric...
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Psychiatric DisordersMedically supervised ketogenic diet as an adjunctive treatment for moderate to severe depression: A pilot study
Major depressive disorder is a prevalent and often treatment-resistant psychiatric condition, frequently co-occurring with metabolic dysfunction. Given growing interest in metabolic interventions, this pilot study explored...
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